Post by wanderlust on Jan 16, 2015 10:23:20 GMT -5
I'm planning to talk to my RE about this (appointment to go over my plan once I get off the bench next month) ....but how worried should I be that my AMH dropped from 4.22 ng/ml (10/13) to 2.67 ng/ml (drawn a few days ago)? FSH and estradiol on day 3 were 8.1 and 61. I know that my AMH is still in the normal range (for now). But I'm getting so anxious thinking that it might start to drop even further soon as I approach 35 in May. I suppose a drop in AMH is to be expected over time but in a little over a year it seems to have dropped quite a bit.
Sigh* ....I hate trying to make sense of all this on my own. My mind seems to automatically go into "worst case scenario" mode.
Uterine fibroids (removed by robotic myomectomy 11/14) and past removal of L ovary/tube d/t ovarian torsion (4/99). New diagnosis of endometriosis (5/15)
Post by bootsorhearts on Jan 16, 2015 10:55:08 GMT -5
I wouldn't worry about it. In theory, AMH is a measure that should only go down over time, but I've seen lots of examples where it goes up. Now, we know we can't like, grow new eggs, so I think what it comes down to is the test is not really all that accurate so you can't put too much stock in any one number. I've read that it's not a good measure of your total egg inventory, only the next batch of follicles that are being prepared for growth and since antral follicle count can very greatly cycle to cycle, I would guess that does too.
I wouldn't read too much into that just yet. We're about the same age and in our age range 4.22 was on the higher side and my RE said anything over 4 they see it as evidence that you could over respond. So you're in the golden range! Even though they say that AMH varies very little with repeat testing, it can still depend on what CD it was drawn on compared to the prior test, as well as varying month-to-month. It can also vary depending on whether or not you used a different lab the second time.
One more thing. If you've made any lifestyle changes or added or subtracted any supplements (like vitamin D) it can also have an effect on AMH.
Married 10 years. DX: AMA, DOR, endo, one tube, +NK, homozygous MTHFR C677T, and abnormal endometrial function test. MFI with high DNA fragmentation and pericentric inversion on chromosome 9.
I wouldn't worry much. Your AMH is still in the "normal" range. If it makes you feel better I would talk to your RE, but I am guessing he will feel the same way. My AMH is around 1.5 I believe and am only 23. My doctor is still optimistic about a BFP in the future. Keep on believing!!
Me:24 DH:27 Married: 12/15/12 BFP May 2014 from IUI #2 after 8 months TTC B/G/G triplets born on 10/22/2015 at 25w5d After a total of 140 days in the NICU all three of my miracles came home!
Post by wanderlust on Jan 16, 2015 15:13:19 GMT -5
Thank you ladies. At times IF makes me react inwardly to things in catastrophic proportions that may not be as hopeless as they seem to me. I will definitely talk to my RE about it ...my biggest question is whether he thinks I should try IUI again (and how many more cycles? I did 3 cycles before surgery last year) or go to IVF.
lemonliz - Is there anything specific you've heard/read about vitamin D and its effects on AMH? I'm intrigued because I did start taking D over the last month.
Uterine fibroids (removed by robotic myomectomy 11/14) and past removal of L ovary/tube d/t ovarian torsion (4/99). New diagnosis of endometriosis (5/15)
I agree with lemonliz re: Vitamin D. My D levels were low, which can artificially suppress your AMH reading. Once I started supplementing Vitamin D and my levels were getting back to the normal range, my AMH reading nearly doubled.
Married 10 years. DX: AMA, DOR, endo, one tube, +NK, homozygous MTHFR C677T, and abnormal endometrial function test. MFI with high DNA fragmentation and pericentric inversion on chromosome 9.
Uterine fibroids (removed by robotic myomectomy 11/14) and past removal of L ovary/tube d/t ovarian torsion (4/99). New diagnosis of endometriosis (5/15)
Post by tumbleweed on Jan 16, 2015 18:34:41 GMT -5
vballbaby I would def get your vitamin D tested. It's really important for many things, including fertility. That along with thryroid are simple tests that lots of docs skip.
Post by QuitcherBitchin on Jan 16, 2015 19:23:37 GMT -5
I second what others have said. Your AMH is still very good, and to be honest, I'm not even convinced that it's a proven measurement of your actual ovarian reserve. My first AMH test came back at .63, but a year later it was .74... and we know it's not possible to produce more eggs, so what does that number really mean?
Also, as low as these numbers are, I still got 7 eggs and 7 embryos that made it to freeze, and my cycle wasn't even that aggressive.
ETA: I turn 33 in a few months, in case you are trying to compare ages and AMHs (but trust me, it's not relevant).
Me 34 w/ .44 AMH, DH 42 w/ low motility after reversed vasectomy 3 failed IUIs in 2012, Military deployment all of 2013, 3 failed IUIs in 2014 ER September 2014, froze 7 embryos FET #1 11/19/2014- BFN FET #2 2/9/2015- CP ER w/ 3dt July 2015- Retrieved 4 embryos, BFN IVF #3 in May 2017!!
vballbaby I would def get your vitamin D tested. It's really important for many things, including fertility. That along with thryroid are simple tests that lots of docs skip.
Yea I just checked my ppw and no mention of Vit D. They did test my thyroid (I think that's the TSH and Thyroid Antibodies). I will check it out. I'm thinking all the volleyball in the Florida sun would have me ok on Vit D plus the multi vitamin??
vballbaby I would def get your vitamin D tested. It's really important for many things, including fertility. That along with thryroid are simple tests that lots of docs skip.
Yea I just checked my ppw and no mention of Vit D. They did test my thyroid (I think that's the TSH and Thyroid Antibodies). I will check it out. I'm thinking all the volleyball in the Florida sun would have me ok on Vit D plus the multi vitamin??
You never know -- I have a mutation that causes me to not process D as well as most people. My mom has this too, so I'm guessing that's where it came from. Even in the summer, I need massive supplementation.
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