Injects and TI??

[snd1231]

Hey ladies.
So as normal, my body likes to be completely uncooperative and unresponsive.
As most of you know last month I was on Femara 2.5 and Estradoil 2mg 2x a day and did not O even with the trigger shot- If you didn't see my post on the other place- I was monitored until I was at 17mm but was going to Mexico for a cruise and couldn't go back for another u/s. They checked my LH level and had me do OPK's and then trigger two days later.)
This cycle they upped my Femara to 5mg and estradoil to 2mg 1x day. On CD 13 I had 2-12s and 4-8s. The RE was not happy at all and told me he didn't think I would have any mature follicles this month. I go back on Wednesday CD18 to see if any mature and if not he will not let me trigger as he believes an O after CD18 isn't effective or beneficial. Anyhow he told me that his next step if I do not respond would be to go to 7.5 mg of Femara and see what happened or possibly injects. I just want some advice on what you ladies think. Would injects give us a better chance of me responding compared to the Femara 7.5mg? Cost isn't really an issue as my insurance covers all the meds with only a $50 co pay for a whole months worth of meds.
I feel like I am not getting anywhere and I haven't even had a chance of a BFP yet. The first month I had a follicle but my lining was way too thin, second month no O at all, and now this month a slow or no response. I want to do something, anything to just have a month were a BFP is possible. Because right now I feel like nothing is working and I am a bit down to be honest.
I would love yall's advice and/or suggestions. I am open to anything!!
I also take fish oil, baby asprin, prenatal, calcium, and vitamin d daily.  I have also tried the raspberry leaf tea and have not seen any improvements on my thin lining.

[lillee]

It's so frustrating when your body doesn't respond like you want it too. I'm sorry
My first cycle was 10mg of Femara + trigger and I didn't respond well. The next cycle they started me on Femara + injects and I responded much better.

[snd1231]

lillee thanks! I hope I will respond better. I always feel better when other people have positive stories and encouragement.

@buttmonkey first of all your avatar is cracking me up!! Love it! I am afraid of overresponse which is why I was questioning it over Femara 7.5. How many follicles did you normally have on just the Clomid? I have never had more than one mature each cycle.ETA I also have low AMH so I think that's why the RE wasn't too concerned with overresponse. Just guessing.

[snd1231]

@buttmonkey I love it I think it is perfect!! Especially since that was always what I pictured when I read your name.

That is a great response! That makes me feel better. I barely have responded each cycle, so I doubt I will have the same issue. I think injects would be great next step for me with my situation. At least you knew that you have a great response to injects for your IVF !! Good luck on your FET!

[bluefairy5]

I'm sorry this is yet another frustrating cycle for you. The only reason my RE didn't want to let us do injects TI/IUI was because of my ridiculous AMH level making me a prime candidate for over-response to injects. (They're practically starting me on IUI doses for IVF as is.)

Injects/TI does sound like it could be a great option for you. And that's awesome that your insurance covers those meds!

[bandm14]

Hey snd1231! I'm so sorry that this cycle is turning out to be frustrating for you again, I know that you have been dealing with a lot. I just met with my RE this week and he discussed Femara vs. injects. One interesting thing that he told me that I did not know is that injects are much better for your lining... not just thickness, but also quality. He said that by Femara blocking estrogen it can affect how the cells are developing in the lining, but since the injects don't block the estrogen (they just add more FSH), this doesn't happen. He also said that statistically success rates are much higher with injects than Femara. If I were you, I would totally go for it! It sounds like you might have a better response from your ovaries, and it also might lead to a better lining situation than you have had in the past.

Good luck!!

[sammae]

Hey! Glad to see you've made it over! Sorry you're having so much trouble getting your response right. Your body's a pain in your ass!!
I have low AMH and I know my RE uses this as the reason why he's putting me on high dosage meds. He said that Clomid/Letrozole would not produce a good enough response in someone with low AMH. He also said I'm not really an OHSS risk due to low AMH being less likely to have things get out of hand.

I say go for it! It sounds like it would be better for your lining too!

[NariaDreaming]

With the low AMH I definitely say go for it, especially since you have coverage!

[fightersince83]

If your insurance covers the cost, then try injects! My RE had me do oral meds + injects but some do injects only. I was also OOP so it was nice to not have to pay for as many injects.

[BunnyBerry]

I never thought overresponse was such a big deal with injects - that's what all those blood draws are for, right? - but then I overresponded last month, and my CD10 ultrasound just showed another 6 all on track together to mature after they supposedly adjusted. So perhaps trying for the Femara 7.5mg at least once would be worth a "shot"? But then again, does your RE think you would be prone to overresponse? If not, and insurance covers it, then I would probably choose injects next to make sure, as you put it, that you actually get your chance of a BFP!

I hope you show a response this cycle after all, though.

[lemonliz]

I just wanted to add that I was obviously on injects this cycle and my lining was "gorgeous" according to RE. So FX for that! I wouldn't worry about over responding on injects. They can tailor the dosage with your AMH level.

[hrushka]

I'm sorry you've been having such frustrating cycles. If I were you, I think I'd want to give injects a try. It's great that your insurance covers it!

[luchich]

I just want to say that $50 for injects is amazing! I just started injects after 3 rounds of clomid and it cost me $415!! Good luck, I hope you find success in them!

[luchich]

Good LUCK! You'll need it! Go Pats!

[bandm14]

Ahhh BunnyBerry I'm so sorry things are turning out the same this cycle... Maybe your E2 levels won't be as high so they won't have to cancel? So frustrating though, sorry girl . I'm a little nervous about over responding now, I hope they start me really low (if this cycle is a BFN, which I have a feeling it will be).

[snd1231]

I am so sorry to responding to you all so late. My grandmother was super sick and I had to take her to the ER this weekend, so needless to say I haven't had much time to get on!

Thank you ladies for the support and advice! I have been thinking injects would be a great next step since my insurance does cover it for really cheap on my end.

bandm14 I had heard that they help with lining but wasn't sure as to why, so thank you! I have had horrible thin lining each month so it would be great to actually have a thick lining for once and if I responded it would be even better!

sammae My body really is a pain! We are in the same boat with low AMH. My RE didn't seem to think over response would be an issue.

BunnyBerry sorry you seem to be over responding again!! Our bodies need to get it together! I see where you are coming from with trying the 7.5 first. Ultimately I will let the RE decide what he wants to do. He didn't seem like over response was something he was remotely concerned about since I haven't responded good or even average to anything yet.

lemonliz I didn't know that they would adjust dosage based on AMH. I learn something new every day!

luchich My insurance has been great! They cover 100% monitoring, labwork,and dr visits. I pay about $50 for injects and Ovidrel but Estradoil, Femara, and Clomid are free. But they do not cover any actual procedures like sperm washing or IUI or IVF retrieval or transfer. So it definitely has its limits.

[bluefairy5]

I'm sorry to hear about your grandma snd1231! I hope she's doing better, or at least comfortable at the moment.

[snd1231]

thanks bluefairy5 she is finally doing better. She went back to her normal doctor and seems to be on the mend but still can't be left alone. Looks like I will be spending the day with her tomorrow.